A brave new world of RNA-binding proteins
RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …
Understanding tumour endothelial cell heterogeneity and function from single-cell omics
Anti-angiogenic therapies (AATs) are used to treat different types of cancers. However, their
success is limited owing to insufficient efficacy and resistance. Recently, single-cell omics …
success is limited owing to insufficient efficacy and resistance. Recently, single-cell omics …
OrthoVenn3: an integrated platform for exploring and visualizing orthologous data across genomes
Advancements in comparative genomics research have led to a growing interest in studying
species evolution and genetic diversity. To facilitate this research, OrthoVenn3 has been …
species evolution and genetic diversity. To facilitate this research, OrthoVenn3 has been …
Complex heatmap visualization
Z Gu - Imeta, 2022 - Wiley Online Library
Heatmap is a widely used statistical visualization method on matrix‐like data to reveal
similar patterns shared by subsets of rows and columns. In the R programming language …
similar patterns shared by subsets of rows and columns. In the R programming language …
The connectome of an insect brain
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
Comparison and evaluation of statistical error models for scRNA-seq
Background Heterogeneity in single-cell RNA-seq (scRNA-seq) data is driven by multiple
sources, including biological variation in cellular state as well as technical variation …
sources, including biological variation in cellular state as well as technical variation …
[HTML][HTML] Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: a report from the COVID-19 and Cancer …
Background Patients with cancer may be at high risk of adverse outcomes from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort of …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We analyzed a cohort of …
Xylazine spreads across the US: a growing component of the increasingly synthetic and polysubstance overdose crisis
Background Sharp exacerbations of the US overdose crisis are linked to polysubstance use
of synthetic compounds. Xylazine is a veterinary tranquilizer, long noted in the street opioid …
of synthetic compounds. Xylazine is a veterinary tranquilizer, long noted in the street opioid …
Multivariable association discovery in population-scale meta-omics studies
It is challenging to associate features such as human health outcomes, diet, environmental
conditions, or other metadata to microbial community measurements, due in part to their …
conditions, or other metadata to microbial community measurements, due in part to their …
ggVennDiagram: an intuitive, easy-to-use, and highly customizable R package to generate Venn diagram
Venn diagrams are widely used diagrams to show the set relationships in biomedical
studies. In this study, we developed ggVennDiagram, an R package that could automatically …
studies. In this study, we developed ggVennDiagram, an R package that could automatically …