TP53 is a critical tumor-suppressor gene that is mutated in more than half of all human
cancers. Mutations in TP53 not only impair its antitumor activity, but also confer mutant p53 …

Gene maps, or annotations, enable us to navigate the functional landscape of our genome.
They are a resource upon which virtually all studies depend, from single-gene to genome …

Abstract The UCSC Genome Browser (https://genome. ucsc. edu) is a graphical viewer for
exploring genome annotations. For almost two decades, the Browser has provided …

While long non-coding RNA (lncRNA) research in the past has primarily focused on the
discovery of novel genes, today it has shifted towards functional annotation of this large …

Abstract Ribosome profiling (Ribo-Seq) has proven transformative for our understanding of
the human genome and proteome by illuminating thousands of noncanonical sites of …

LncRNA–miRNA interactions contribute to the regulation of therapeutic targets and
diagnostic biomarkers in multifarious human diseases. However, it remains difficult to …

Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …

Abstract NONCODE (http://www. bioinfo. org/noncode/) is a systematic database that is
dedicated to presenting the most complete collection and annotation of non-coding RNAs …

Advances in the depth and quality of transcriptome sequencing have revealed many new
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …

LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …