[HTML][HTML] Fungal vaccines, mechanism of actions and immunology: A comprehensive review

S Nami, R Mohammadi, M Vakili, K Khezripour… - Biomedicine & …, 2019 - Elsevier
Fungal infections include a wide range of opportunistic and invasive diseases. Two of four
major fatal diseases in patients with human immunodeficiency virus (HIV) infection are …

Harnessing the immune response to fungal pathogens for vaccine development

A Rivera, J Lodge, C Xue - Annual review of microbiology, 2022 - annualreviews.org
Invasive fungal infections are emerging diseases that kill over 1.5 million people per year
worldwide. With the increase of immunocompromised populations, the incidence of invasive …

Proteomics Unravels Extracellular Vesicles as Carriers of Classical Cytoplasmic Proteins in Candida albicans

A Gil-Bona, A Llama-Palacios, CM Parra… - Journal of proteome …, 2015 - ACS Publications
The commensal fungus Candida albicans secretes a considerable number of proteins and,
as in different fungal pathogens, extracellular vesicles (EVs) have also been observed. Our …

Vaccines against candidiasis: Status, challenges and emerging opportunity

SR Sahu, S Bose, M Singh, P Kumari… - Frontiers in Cellular …, 2022 - frontiersin.org
Candidiasis is a mycosis caused by opportunistic Candida species. The occurrence of
fungal infections has considerably increased in the last few years primarily due to an …

Moonlighting proteins at the candidal cell surface

D Satala, J Karkowska-Kuleta, A Zelazna… - Microorganisms, 2020 - mdpi.com
The cell wall in Candida albicans is not only a tight protective envelope but also a point of
contact with the human host that provides a dynamic response to the constantly changing …

Candida albicans hyphal extracellular vesicles are different from yeast ones, carrying an active proteasome complex and showing a different role in host immune …

R Martínez-López, ML Hernáez, E Redondo… - Microbiology …, 2022 - Am Soc Microbiol
Candida albicans is the principal causative agent of lethal fungal infections, predominantly
in immunocompromised hosts. Extracellular vesicles (EVs) have been described as crucial …

Application of anti-fungal vaccines as a tool against emerging anti-fungal resistance

R Kumar, V Srivastava - Frontiers in Fungal Biology, 2023 - frontiersin.org
After viruses and bacteria, fungal infections remain a serious threat to the survival and well-
being of society. The continuous emergence of resistance against commonly used anti …

The Elusive Anti-Candida Vaccine: Lessons From the Past and Opportunities for the Future

GHW Tso, JA Reales-Calderon, N Pavelka - Frontiers in Immunology, 2018 - frontiersin.org
Candidemia is a bloodstream fungal infection caused by Candida species and is most
commonly observed in hospitalized patients. Even with proper antifungal drug treatment …

Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10

L Schild, A Heyken, PWJ de Groot, E Hiller… - Eukaryotic …, 2011 - Am Soc Microbiol
The cell wall of the human-pathogenic fungus Candida albicans is a robust but also dynamic
structure which mediates adaptation to changing environmental conditions during infection …

[HTML][HTML] Cell wall associated proteins involved in filamentation with impact on the virulence of Candida albicans

GS Arita, DR Faria, IRG Capoci, ES Kioshima… - Microbiological …, 2022 - Elsevier
Candida albicans is a commensal microorganism of the human microbiota that can be
associated with superficial to disseminated infections. This species possesses several …