Photophysical mechanisms of photobiomodulation therapy as precision medicine

A Liebert, W Capon, V Pang, D Vila, B Bicknell… - Biomedicines, 2023 - mdpi.com
Despite a significant focus on the photochemical and photoelectrical mechanisms
underlying photobiomodulation (PBM), its complex functions are yet to be fully elucidated …

Devices used for photobiomodulation of the brain—a comprehensive and systematic review

F Fernandes, S Oliveira, F Monteiro, M Gasik… - Journal of …, 2024 - Springer
A systematic review was conducted to determine the trends in devices and parameters used
for brain photobiomodulation (PBM). The revised studies included clinical and cadaveric …

Photobiomodulation and nitric oxide signaling

S Kashiwagi, A Morita, S Yokomizo, E Ogawa, E Komai… - Nitric Oxide, 2023 - Elsevier
Nitric oxide (NO) is a well-known gaseous mediator that maintains vascular homeostasis.
Extensive evidence supports that a hallmark of endothelial dysfunction, which leads to …

Near-infrared II photobiomodulation preconditioning ameliorates stroke injury via phosphorylation of eNOS

S Yokomizo, T Kopp, M Roessing, A Morita, S Lee… - Stroke, 2024 - ahajournals.org
BACKGROUND: The current management of patients with stroke with intravenous
thrombolysis and endovascular thrombectomy is effective only when it is timely performed …

Photobiomodulation enhances memory processing in older adults with mild cognitive impairment: a functional near-infrared spectroscopy study

AS Chan, T Lee, MR Hamblin… - Journal of Alzheimer's …, 2021 - journals.sagepub.com
Background: Recent studies of photobiomodulation (PBM) in patients with cognitive or
psychological disorders (including traumatic brain injury, stroke, and dementia) have yielded …

The effect of photobiomodulation on the brain during wakefulness and sleep

C Moro, A Valverde, M Dole, J Hoh Kam… - Frontiers in …, 2022 - frontiersin.org
Over the last seventy years or so, many previous studies have shown that
photobiomodulation, the use of red to near infrared light on body tissues, can improve …

Transcranial photobiomodulation in children aged 2–6 years: A randomized sham-controlled clinical trial assessing safety, efficacy, and impact on autism spectrum …

Y Fradkin, L De Taboada, M Naeser… - Frontiers in …, 2024 - frontiersin.org
Background Small pilot studies have suggested that transcranial photobiomodulation (tPBM)
could help reduce symptoms of neurological conditions, such as depression, traumatic brain …

Transcranial photobiomodulation and thermal stimulation induce distinct topographies of EEG alpha and beta power changes in healthy humans

X Wang, H Wanniarachchi, A Wu, F Gonzalez-Lima… - Scientific reports, 2021 - nature.com
Our recent study demonstrated that prefrontal transcranial photobiomodulation (tPBM) with
1064-nm laser enables significant changes in EEG rhythms, but these changes might result …

Photobiomodulation for the aging brain

F dos Santos Cardoso, F Gonzalez-Lima… - Ageing Research …, 2021 - Elsevier
Longevity is one of the great triumphs of humanity. Worldwide, the elderly is the fastest
growing segment of the population. As a consequence, the number of cases of age-related …

Mechanistic aspects of photobiomodulation therapy in the nervous system

F Ramezani, A Neshasteh-Riz, A Ghadaksaz… - Lasers in Medical …, 2022 - Springer
Photobiomodulation therapy (PBMT) previously known as low-level laser therapy (LLLT) has
been used for over 30 years, to treat neurological diseases. Low-powered lasers are …