Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune
response in a very complex and flowery manner. The history of host-parasite co-evolution …

Chagas disease is an important neglected disease that affects 6–7 million people
worldwide. The disease has two phases: acute and chronic, in which there are different …

Post-infectious conditions present major health burdens but remain poorly understood. In
Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that …

Deregulated CD8+ T cell cytotoxicity plays a central role in enhancing disease severity in
several conditions. However, we have little understanding of the mechanisms by which …

In this chapter, the main prognostic markers of Chagas heart disease are addressed, with an
emphasis on the most recent findings and questions, establishing the basis for a broad …

Chronic Chagas disease cardiomyopathy (CCC), an especially aggressive inflammatory
dilated cardiomyopathy caused by lifelong infection with the protozoan Trypanosoma cruzi …

Chagas disease is a neglected tropical disease transmitted by the protozoan Trypanosoma
cruzi that lately has been highlighted because several outbreaks attributed to oral …

Chagas disease, a neglected disease caused by the protozoan Trypanosoma cruzi, is
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …

The definition of a biomarker provided by the World Health Organization is any substance,
structure, or process that can be measured in the body, or its products and influence, or …

Chagas disease, caused by the parasite Trypanosoma cruzi (T. cruzi), remains a serious
public health problem for which there is no effective treatment in the chronic stage. Intense …