Learning with limited annotations: a survey on deep semi-supervised learning for medical image segmentation

R Jiao, Y Zhang, L Ding, B Xue, J Zhang, R Cai… - Computers in Biology …, 2024 - Elsevier
Medical image segmentation is a fundamental and critical step in many image-guided
clinical approaches. Recent success of deep learning-based segmentation methods usually …

Astrocyte morphology

KT Baldwin, KK Murai, BS Khakh - Trends in cell biology, 2024 - cell.com
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal
feature of astrocytes is their complex and visually enchanting morphology, referred to as …

Whole-cell organelle segmentation in volume electron microscopy

L Heinrich, D Bennett, D Ackerman, W Park, J Bogovic… - Nature, 2021 - nature.com
Cells contain hundreds of organelles and macromolecular assemblies. Obtaining a
complete understanding of their intricate organization requires the nanometre-level, three …

A connectome and analysis of the adult Drosophila central brain

LK Scheffer, CS Xu, M Januszewski, Z Lu, S Takemura… - elife, 2020 - elifesciences.org
The neural circuits responsible for animal behavior remain largely unknown. We summarize
new methods and present the circuitry of a large fraction of the brain of the fruit fly …

A connectomic study of a petascale fragment of human cerebral cortex

A Shapson-Coe, M Januszewski, DR Berger, A Pope… - BioRxiv, 2021 - biorxiv.org
We acquired a rapidly preserved human surgical sample from the temporal lobe of the
cerebral cortex. We stained a 1 mm3 volume with heavy metals, embedded it in resin, cut …

Whole-animal connectomes of both Caenorhabditis elegans sexes

SJ Cook, TA Jarrell, CA Brittin, Y Wang, AE Bloniarz… - Nature, 2019 - nature.com
Abstract Knowledge of connectivity in the nervous system is essential to understanding its
function. Here we describe connectomes for both adult sexes of the nematode …

[HTML][HTML] Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity

NL Turner, T Macrina, JA Bae, R Yang, AM Wilson… - Cell, 2022 - cell.com
We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

Quantitative magnetic resonance imaging of brain anatomy and in vivo histology

N Weiskopf, LJ Edwards, G Helms… - Nature Reviews …, 2021 - nature.com
Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …

Connectomes across development reveal principles of brain maturation

D Witvliet, B Mulcahy, JK Mitchell, Y Meirovitch… - Nature, 2021 - nature.com
An animal's nervous system changes as its body grows from birth to adulthood and its
behaviours mature,,,,,,–. The form and extent of circuit remodelling across the connectome is …

The emerging nature of astrocyte diversity

BS Khakh, B Deneen - Annual review of neuroscience, 2019 - annualreviews.org
Astrocytes are morphologically complex, ubiquitous cells that are viewed as a
homogeneous population tiling the entire central nervous system (CNS). However, this view …