Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

In view of the importance of molecular sensing in the function of the gastrointestinal (GI)
tract, we assessed whether signal transduction proteins that mediate taste signaling are …

Type II collagen is composed of α1 (II) chains encoded by the COL2A1 gene. Alteration of
this cartilage marker is a common feature of osteoarthritis. Interleukin-6 (IL-6) is a pro …

GDF5 encodes an extracellular signalling molecule that is essential for normal skeletal
development. The rs144383 C to T SNP located in the 5ʹUTR of this gene is functional and …

The catechol‐o‐methyltransferase (COMT) gene on chromosome 22q11 has been
considered a strong candidate gene for schizophrenia (SZ) susceptibility. A functional …

Gene expression programs required for differentiation depend on both DNA-bound
transcription factors and surrounding histone modifications. Expression of the basic helix …

Kisspeptins are natural ligands of G protein-coupled receptor-54. Activation of KiSS1/G
protein-coupled receptor-54 signaling pathways results in potent activation of the …

The discovery of secretin initiated the field of endocrinology. Over the past century, multiple
gastrointestinal functions of secretin have been extensively studied, and it was discovered …

The gene encoding the ABCC6 protein, an ABC transporter of the multidrug resistance-
associated protein (MRP), is mainly expressed in liver and kidney. Mutations in ABCC6 are …