Molecular and neuronal substrates for general anaesthetics
Although general anaesthesia has been of tremendous importance for the development of
surgery, the underlying mechanisms by which this state is achieved are only just beginning …
surgery, the underlying mechanisms by which this state is achieved are only just beginning …
A narrative review on clinical applications of fNIRS
Functional near-infrared spectroscopy (fNIRS) is a relatively new imaging modality in the
functional neuroimaging research arena. The fNIRS modality non-invasively investigates the …
functional neuroimaging research arena. The fNIRS modality non-invasively investigates the …
The fMRI signal, slow cortical potential and consciousness
As functional magnetic resonance imaging (fMRI) has become a driving force in cognitive
neuroscience, it is crucial to understand the neural basis of the fMRI signal. Here, we …
neuroscience, it is crucial to understand the neural basis of the fMRI signal. Here, we …
Neural systems for speech and song in autism
Despite language disabilities in autism, music abilities are frequently preserved.
Paradoxically, brain regions associated with these functions typically overlap, enabling …
Paradoxically, brain regions associated with these functions typically overlap, enabling …
Dissociating speech perception and comprehension at reduced levels of awareness
We used functional MRI and the anesthetic agent propofol to assess the relationship among
neural responses to speech, successful comprehension, and conscious awareness …
neural responses to speech, successful comprehension, and conscious awareness …
Functional connectivity and alterations in baseline brain state in humans
This work examines the influence of changes in baseline activity on the intrinsic functional
connectivity fMRI (fc-fMRI) in humans. Baseline brain activity was altered by inducing …
connectivity fMRI (fc-fMRI) in humans. Baseline brain activity was altered by inducing …
The role of fMRI in drug discovery
Pharmacological functional (phMRI) studies are making a significant contribution to our
understanding of drug‐effects on brain systems. Pharmacological fMRI has an additional …
understanding of drug‐effects on brain systems. Pharmacological fMRI has an additional …
Disconnecting consciousness: is there a common anesthetic end point?
In this article, we review (1) the importance of information integration in consciousness,(2)
early studies of network breakdown during anesthesia,(3) preclinical research …
early studies of network breakdown during anesthesia,(3) preclinical research …
Baseline brain energy supports the state of consciousness
An individual, human or animal, is defined to be in a conscious state empirically by the
behavioral ability to respond meaningfully to stimuli, whereas the loss of consciousness is …
behavioral ability to respond meaningfully to stimuli, whereas the loss of consciousness is …
Propofol disrupts functional interactions between sensory and high‐order processing of auditory verbal memory
Current theories suggest that disrupting cortical information integration may account for the
mechanism of general anesthesia in suppressing consciousness. Human cognitive …
mechanism of general anesthesia in suppressing consciousness. Human cognitive …