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Natural products as multidrug resistance modulators in cancer
Cancer is a prominent cause of death globally. Currently, many drugs that are in clinical
practice are having a high prevalence of side effect and multidrug resistance. Risk of tumors …
practice are having a high prevalence of side effect and multidrug resistance. Risk of tumors …
The metabolism of berberine and its contribution to the pharmacological effects
K Wang, X Feng, L Chai, S Cao, F Qiu - Drug metabolism reviews, 2017 - Taylor & Francis
Berberine, a bioactive alkaloid isolated from several herbal substances, possesses multiple
pharmacological effects, including antimicrobial, antidiabetic, anticancer activities …
pharmacological effects, including antimicrobial, antidiabetic, anticancer activities …
Flavonoids and gastrointestinal health: single molecule for multiple roles
H Lan, H Wang, C Chen, W Hu, C Ai… - Critical Reviews in …, 2024 - Taylor & Francis
Diet can be considered as one of the pivotal factors in regulating gastrointestinal health, and
polyphenols widely distributed in human daily diet. The polyphenols and their metabolites …
polyphenols widely distributed in human daily diet. The polyphenols and their metabolites …
Membrane interactions of phytochemicals as their molecular mechanism applicable to the discovery of drug leads from plants
H Tsuchiya - Molecules, 2015 - mdpi.com
In addition to interacting with functional proteins such as receptors, ion channels, and
enzymes, a variety of drugs mechanistically act on membrane lipids to change the …
enzymes, a variety of drugs mechanistically act on membrane lipids to change the …
Inhibition of α-glucosidase and α-amylase by flavonoid glycosides from Lu'an GuaPian tea: molecular docking and interaction mechanism
F Hua, P Zhou, HY Wu, GX Chu, ZW ** solid oral …, 2017 - Elsevier
To be effective, drugs in an oral dosage form first must be absorbed and then reach the
target organs via systemic circulation. Barriers that prevent drugs from reaching the systemic …
target organs via systemic circulation. Barriers that prevent drugs from reaching the systemic …
Gastrointestinal stability of dihydromyricetin, myricetin, and myricitrin: an in vitro investigation
The gastrointestinal (GI) stability of three flavonoids, dihydromyricetin (DMY), myricetin
(MYR), and myricitrin (MYT), was examined in simulated physiological fluids. Several factors …
(MYR), and myricitrin (MYT), was examined in simulated physiological fluids. Several factors …