Our incomplete understanding of the causes and pathways involved in the onset and
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …

Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles
in health and disease. Recent technologies have uncovered the functional heterogeneity of …

Cell–cell interactions in the central nervous system play important roles in neurologic
diseases. However, little is known about the specific molecular pathways involved, and …

Background Several studies have linked gut microbiota to human brain activity. This study
used Mendelian randomization (MR) to investigate the causal relationship between gut …

As one of most common and severe mental disorders, major depressive disorder (MDD)
significantly increases the risks of premature death and other medical conditions for patients …

Selective vulnerability of specific brain regions and cell populations is a hallmark of
neurodegenerative disorders. Mechanisms of selective vulnerability involve neuronal …

Fiber intake is associated with a lower risk for Alzheimer´ s disease (AD) in older adults.
Intake of plant-based diets rich in soluble fiber promotes the production of short-chain fatty …

Glia have emerged as important architects of central nervous system (CNS) development
and maintenance. While traditionally glial contributions to CNS development and …

Oligodendrocytes (ODCs) are myelinating cells of the central nervous system (CNS)
supporting neuronal survival. Oxidants and mitochondrial dysfunction have been suggested …

Dectin-1 is a C-type lectin receptor (CLR) expressed on the surface of various mammalian
myeloid cells. Dectin-1 recognizes β-glucans and elicits antifungal proinflammatory immune …