Functional neuroanatomy of amygdalohippocampal interconnections and their role in learning and memory

AJ McDonald, DD Mott - Journal of neuroscience research, 2017 - Wiley Online Library
The amygdalar nuclear complex and hippocampal/parahippocampal region are key
components of the limbic system that play a critical role in emotional learning and memory …

Neurodegenerative processes in temporal lobe epilepsy with hippocampal sclerosis: Clinical, pathological and neuroimaging evidence

XY Tai, B Bernhardt, M Thom… - Neuropathology and …, 2018 - Wiley Online Library
Cognitive decline is increasingly described as a co‐morbidity of temporal lobe epilepsy
(TLE). Mechanisms underlying cognitive impairment are not fully understood despite …

Beyond localization: the role of traditional neuropsychological tests in an age of imaging

S Baxendale, P Thompson - Epilepsia, 2010 - Wiley Online Library
Rapid advances in structural and functional magnetic resonance imaging (MRI) present two
significant challenges to the rationale and role of the traditional neuropsychological …

Cognitive deterioration in adult epilepsy: Does accelerated cognitive ageing exist?

LEM Breuer, P Boon, JWM Bergmans, WH Mess… - Neuroscience & …, 2016 - Elsevier
A long-standing concern has been whether epilepsy contributes to cognitive decline or so-
called 'epileptic dementia'. Although global cognitive decline is generally reported in the …

[HTML][HTML] Brain aging in temporal lobe epilepsy: Chronological, structural, and functional

G Hwang, B Hermann, VA Nair, LL Conant, K Dabbs… - NeuroImage: Clinical, 2020 - Elsevier
The association of epilepsy with structural brain changes and cognitive abnormalities in
midlife has raised concern regarding the possibility of future accelerated brain and cognitive …

Surgical versus medical treatment for refractory epilepsy: outcomes beyond seizure control

MS Perry, M Duchowny - Epilepsia, 2013 - Wiley Online Library
Nearly one third of patients with epilepsy become medically intractable, and the likelihood of
achieving seizure freedom decreases with each additional medication trial. For …

Methods and utility of EEG-fMRI in epilepsy

LA van Graan, L Lemieux… - Quantitative imaging in …, 2015 - pmc.ncbi.nlm.nih.gov
Brain activity data in general and more specifically in epilepsy can be represented as a
matrix that includes measures of electrophysiology, anatomy and behaviour. Each of these …

Real-life memory and spatial navigation in patients with focal epilepsy: ecological validity of a virtual reality supermarket task

P Grewe, D Lahr, A Kohsik, E Dyck, HJ Markowitsch… - Epilepsy & Behavior, 2014 - Elsevier
Ecological assessment and training of real-life cognitive functions such as visual–spatial
abilities in patients with epilepsy remain challenging. Some studies have applied virtual …

Comparing the Wada test and functional MRI for the presurgical evaluation of memory in temporal lobe epilepsy

A Massot-Tarrús, K White, SM Mirsattari - Current neurology and …, 2019 - Springer
Abstract Purpose of Review The usefulness of the Wada test (WT) predicting memory
impairment from temporal lobe epilepsy (TLE) surgery has been debated, and it has …

Brain structure and aging in chronic temporal lobe epilepsy

K Dabbs, T Becker, J Jones, P Rutecki… - …, 2012 - Wiley Online Library
Purpose: To characterize differences in brain structure and their patterns of age‐related
change in individuals with chronic childhood/adolescent onset temporal lobe epilepsy …