How to explain the beneficial effects of leukocyte‐and platelet‐rich fibrin

J Blanco, A García, L Hermida‐Nogueira… - Periodontology …, 2024 - Wiley Online Library
The survival of an organism relies on its ability to repair the damage caused by trauma, toxic
agents, and inflammation. This process involving cell proliferation and differentiation is …

How to explain the beneficial effects of platelet‐rich plasma

R Gruber - Periodontology 2000, 2025 - Wiley Online Library
Platelet‐rich plasma (PRP) is the platelet and leukocyte‐containing plasmatic fraction of
anticoagulated autologous blood. While evidence supporting the clinical use of PRP in …

[HTML][HTML] Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis

Y Takahata, H Hagino, A Kimura, M Urushizaki… - International Journal of …, 2022 - mdpi.com
Owing to the rapid aging of society, the numbers of patients with joint disease continue to
increase. Accordingly, a large number of patients require appropriate treatment for …

Autologous platelet concentrates in root coverage procedures

S Barootchi, L Tavelli, MEG Vinueza… - Periodontology …, 2024 - Wiley Online Library
Gingival recessions are vastly prevalent among the general population. With regards to their
treatment, recent advancements in periodontal and microsurgical procedures, focusing on …

Lipids of platelet-rich fibrin reduce the inflammatory response in mesenchymal cells and macrophages

Z Kargarpour, L Panahipour, M Mildner, RJ Miron… - Cells, 2023 - mdpi.com
Platelet-rich fibrin (PRF) has a potent anti-inflammatory activity but the components
mediating this effect remain unknown. Blood lipids have anti-inflammatory properties. The …

[HTML][HTML] Platelet-rich fibrin decreases the inflammatory response of mesenchymal cells

Z Kargarpour, J Nasirzade, L Panahipour… - International journal of …, 2021 - mdpi.com
Chronic inflammation is a pathological process where cells of the mesenchymal lineage
become a major source of inflammatory mediators. Platelet-rich fibrin (PRF) has been shown …

[HTML][HTML] Proteomic analysis of mesenchymal stromal cells secretome in comparison to leukocyte-and platelet-rich fibrin

N Al-Sharabi, R Gruber, M Sanz… - International journal of …, 2023 - mdpi.com
Secretomes of mesenchymal stromal cells (MSCs) are emerging as a novel growth factor
(GF)-based strategy for periodontal and bone regeneration. The objective of this study was …

Functionalizing collagen membranes with MSC-conditioned media promotes guided bone regeneration in rat calvarial defects

S Shanbhag, C Kampleitner, N Al-Sharabi… - Cells, 2023 - mdpi.com
Functionalizing biomaterials with conditioned media (CM) from mesenchymal stromal cells
(MSC) is a promising strategy for enhancing the outcomes of guided bone regeneration …

[HTML][HTML] A purified human platelet pellet lysate rich in neurotrophic factors and antioxidants repairs and protects corneal endothelial cells from oxidative stress

R Widyaningrum, T Burnouf, O Nebie, L Delila… - Biomedicine & …, 2021 - Elsevier
Human platelet lysate (HPL) is a complex mixture of potent bioactive molecules instrumental
in tissue repair and regeneration. Due to their remarkable safety, cost-effective production …

Active and Passive Mineralization of Bio-Gide® Membranes in Rat Calvaria Defects

KA Apaza Alccayhuaman, P Heimel, S Tangl… - Journal of Functional …, 2024 - mdpi.com
Bio-Gide® is a collagen membrane routinely used in guided bone regeneration. Recent
studies have shown that this collagen membrane has osteoconductive properties, meaning …