The endoplasmic reticulum (ER) functions as a quality-control organelle for protein
homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated …

Myopia, also known as short-sightedness or near-sightedness, is a very common condition
that typically starts in childhood. Severe forms of myopia (pathologic myopia) are associated …

Purpose To assess the efficacy and safety of repeated low-level red-light (RLRL) therapy in
myopia control in children. Design Multicenter, randomized, parallel-group, single-blind …

Myopic axial elongation is associated with various non-pathological changes. These include
a decrease in photoreceptor cell and retinal pigment epithelium (RPE) cell density and …

The automobile tire antioxidant N-(1, 3-dimethylbutyl)-N'-phenyl-p-phenylenediamine
(6PPD) and its quinone metabolite 6PPDQ have recently received much attention for their …

The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

The choroid is the richly vascular layer of the eye located between the sclera and Bruch's
membrane. Early studies in animals, as well as more recent studies in humans, have …

Importance Myopia is a global concern, but effective prevention measures remain limited.
Premyopia is a refractive state in which children are at higher risk of myopia, meriting …

Myopia is characterized of maladaptive increases in scleral fibroblast-to-myofibroblast
transdifferentiation (FMT). Scleral hypoxia is a significant factor contributing to myopia, but …

PURPOSE To evaluate the long-term efficacy and safety of repeated low-intensity red light
(RLRL) treatment for childhood myopia. DESIGN Systematic review and meta-analysis …