Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …

Acute myocardial infarction (MI) inflicts massive injury to the coronary microcirculation
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …

Skeletal tissue is highly innervated. Although different types of nerves have been recently
identified in the bone, the crosstalk between bone and nerves remains unclear. In this …

Anthracyclines are the cornerstone of many chemotherapy regimens for a variety of cancers.
Unfortunately, their use is limited by a cumulative dose-dependent cardiotoxicity. Despite …

Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Some organisms, such as adult zebrafish and newborn mice, have the capacity to
regenerate heart tissue following injury. Unraveling the mechanisms of heart regeneration is …

A growing body of epidemiological evidence suggested that metabolic syndrome (MetS) and
Mets components (impaired glucose tolerance, abdominal or central obesity, hypertension …

Significance: Proangiogenic therapy appeared a promising strategy for the treatment of
patients with acute myocardial infarction (MI), as de novo formation of microvessels, has the …

One of the greatest examples of integrated signal transduction is revealed by examination of
effects mediated by AKT kinase in myocardial biology. Positioned at the intersection of …

The heart is electrically and mechanically controlled as a syncytium by the autonomic
nervous system. The cardiac nervous system comprises the sympathetic, parasympathetic …