Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022‏ - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Probiotics, prebiotics, and postbiotics in health and disease

J Ji, W **, SJ Liu, Z Jiao, X Li - MedComm, 2023‏ - Wiley Online Library
The gut microbiota and its homeostasis play a crucial role in human health. However, for
some diseases related to the gut microbiota, current traditional medicines can only relieve …

Role of prebiotics, probiotics, and synbiotics in management of inflammatory bowel disease: Current perspectives

S Roy, S Dhaneshwar - World Journal of Gastroenterology, 2023‏ - pmc.ncbi.nlm.nih.gov
Experimental evidence supports the fact that changes in the bowel microflora due to
environmental or dietary factors have been investigated as implicating factors in the …

Microbiota-derived indoles alleviate intestinal inflammation and modulate microbiome by microbial cross-feeding

G Wang, Y Fan, G Zhang, S Cai, Y Ma, L Yang, Y Wang… - Microbiome, 2024‏ - Springer
Background The host–microbiota interaction plays a crucial role in maintaining homeostasis
and disease susceptibility, and microbial tryptophan metabolites are potent modulators of …

The influence of probiotics on the firmicutes/bacteroidetes ratio in the treatment of obesity and inflammatory bowel disease

S Stojanov, A Berlec, B Štrukelj - Microorganisms, 2020‏ - mdpi.com
The two most important bacterial phyla in the gastrointestinal tract, Firmicutes and
Bacteroidetes, have gained much attention in recent years. The Firmicutes/Bacteroidetes …

Diets intervene osteoporosis via gut-bone axis

YW Zhang, PR Song, SC Wang, H Liu, ZM Shi… - Gut Microbes, 2024‏ - Taylor & Francis
Osteoporosis is a systemic skeletal disease that seriously endangers the health of middle-
aged and older adults. Recently, with the continuous deepening of research, an increasing …

Role of gut microbiota in infectious and inflammatory diseases

MF Maciel-Fiuza, GC Muller, DMS Campos… - Frontiers in …, 2023‏ - frontiersin.org
Thousands of microorganisms compose the human gut microbiota, fighting pathogens in
infectious diseases and inhibiting or inducing inflammation in different immunological …

Lactobacillus johnsonii alleviates colitis by TLR1/2-STAT3 mediated CD206+ macrophagesIL-10 activation

DJC Jia, QW Wang, YY Hu, JM He, QW Ge, YD Qi… - Gut …, 2022‏ - Taylor & Francis
Imbalance of gut microbiota homeostasis is related to the occurrence of ulcerative colitis
(UC), and probiotics are thought to modulate immune microenvironment and repair barrier …

Akkermansia muciniphila alleviates dextran sulfate sodium (DSS)-induced acute colitis by NLRP3 activation

S Qu, L Fan, Y Qi, C Xu, Y Hu, S Chen, W Liu… - Microbiology …, 2021‏ - journals.asm.org
Akkermansia muciniphila has been proved to play a crucial role in the progression of colitis,
but its underlying mechanism remains inconclusive. In this study, we aim to investigate the …

Interaction between gut microbiota and sex hormones and their relation to sexual dimorphism in metabolic diseases

JA Santos-Marcos, M Mora-Ortiz… - Biology of sex …, 2023‏ - Springer
Metabolic diseases, such as obesity, metabolic syndrome (MetS) and type 2 diabetes (T2D),
are now a widespread pandemic in the developed world. These pathologies show sex …