Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Diabetes mellitus (DM) is a chronic metabolic condition characterized by persistent
hyperglycemia due to insufficient insulin levels or insulin resistance. Despite the availability …

Obesity is a significant public health problem worldwide that is characterized by abnormal or
excessive fat accumulation. Unfortunately, the application of available weight-loss drugs has …

Background No reports exist as to neuroprotective effects associated with topical activation
of transient receptor potential melastatin 8 (TRPM8), a noted cold receptor. In the present …

The beef quality significantly varies between breeds. **liang Red Cattle resembles
Wagyu in fat deposition and flavor. To screen key factors affecting beef quality, we …

Obesity is a chronic metabolic disease caused by a long-term imbalance between energy
intake and expenditure. The discovery of three different shades of adipose tissues has …

Obesity leads to the development of many metabolic diseases, causing severe health
problems. Menthol can induce adipocyte browning and thus has been used to combat …

Obesity is a complex, chronic and inflammatory disease that affects more than one-third of
the world's population, leading to a higher incidence of diabetes, dyslipidemia, metabolic …

The gut barrier–including tight junction proteins (TJPs) and mucus layers, is the first line of
defense against physical, chemical or pathogenic incursions. This barrier is compromised in …

As one of the main pathogenic factors of cardiovascular and cerebrovascular diseases, the
incidence of metabolic diseases such as adiposity and metabolic dysfunction-associated …