A metabolomics pipeline for the mechanistic interrogation of the gut microbiome
Gut microorganisms modulate host phenotypes and are associated with numerous health
effects in humans, ranging from host responses to cancer immunotherapy to metabolic …
effects in humans, ranging from host responses to cancer immunotherapy to metabolic …
Nanospray Desorption Electrospray Ionization Mass Spectrometry Imaging (nano-DESI MSI): A Tutorial Review
M Iqfath, SN Wali, S Amer, E Hernly… - ACS Measurement …, 2024 - ACS Publications
Nanospray desorption electrospray ionization (nano-DESI) is a liquid-based ambient mass
spectrometry imaging (MSI) technique that enables visualization of analyte distributions in …
spectrometry imaging (MSI) technique that enables visualization of analyte distributions in …
A practical guide to interpreting and generating bottom‐up proteomics data visualizations
Mass‐spectrometry based bottom‐up proteomics is the main method to analyze proteomes
comprehensively and the rapid evolution of instrumentation and data analysis has made the …
comprehensively and the rapid evolution of instrumentation and data analysis has made the …
Predicting glycan structure from tandem mass spectrometry via deep learning
Glycans constitute the most complicated post-translational modification, modulating protein
activity in health and disease. However, structural annotation from tandem mass …
activity in health and disease. However, structural annotation from tandem mass …
Deep learning for the precise peak detection in high-resolution LC–MS data
AD Melnikov, YP Tsentalovich… - Analytical chemistry, 2019 - ACS Publications
This letter is devoted to the application of machine learning, namely, convolutional neural
networks to solve problems in the initial steps of the common pipeline for data analysis in …
networks to solve problems in the initial steps of the common pipeline for data analysis in …
Pyteomics 4.0: five years of development of a python proteomics framework
Many of the novel ideas that drive today's proteomic technologies are focused essentially on
experimental or data-processing workflows. The latter are implemented and published in a …
experimental or data-processing workflows. The latter are implemented and published in a …
Heterogeneously deacetylated chitosans possess an unexpected regular pattern favoring acetylation at every third position
MJ Hellmann, D Gillet, S Trombotto, S Raetz… - Nature …, 2024 - nature.com
Chitosans are promising biopolymers for diverse applications, with material properties and
bioactivities depending ia. on their pattern of acetylation (PA). Commercial chitosans are …
bioactivities depending ia. on their pattern of acetylation (PA). Commercial chitosans are …
Oktoberfest: Open‐source spectral library generation and rescoring pipeline based on Prosit
Abstract Machine learning (ML) and deep learning (DL) models for peptide property
prediction such as Prosit have enabled the creation of high quality in silico reference …
prediction such as Prosit have enabled the creation of high quality in silico reference …
Identification of structural and regulatory cell-shape determinants in Haloferax volcanii
H Schiller, Y Hong, J Kouassi, T Rados, J Kwak… - Nature …, 2024 - nature.com
Archaea play indispensable roles in global biogeochemical cycles, yet many crucial cellular
processes, including cell-shape determination, are poorly understood. Haloferax volcanii, a …
processes, including cell-shape determination, are poorly understood. Haloferax volcanii, a …
MSIGen: an open-source python package for processing and visualizing mass spectrometry imaging data
Mass spectrometry imaging (MSI) provides information about the spatial localization of
molecules in complex samples with high sensitivity and molecular selectivity. Although point …
molecules in complex samples with high sensitivity and molecular selectivity. Although point …