Apicomplexan parasites, such as human malaria parasites, have complex lifecycles
encompassing multiple and diverse environmental niches. Invading, replicating, and …

Plasmodium sporozoite transmission is a critical population bottleneck in parasite life-cycle
progression and, hence, a target for prophylactic drugs and vaccines. The recent progress of …

The phylum Apicomplexa comprises important eukaryotic parasites that invade host tissues
and cells using a unique mechanism of gliding motility. Gliding is powered by actomyosin …

Apicomplexan parasites exhibit tremendous diversity in much of their fundamental cell
biology, but study of these organisms using light microscopy is often hindered by their small …

Microtubules are a ubiquitous eukaryotic cytoskeletal element typically consisting of 13
protofilaments arranged in a hollow cylinder. This arrangement is considered the canonical …

Parasites of the phylum Apicomplexa cause important diseases including malaria,
cryptosporidiosis and toxoplasmosis. These intracellular pathogens inject the contents of an …

Apicomplexan parasites secrete contents of the rhoptries, club-shaped organelles in the
apical region, into host cells to permit their invasion and establishment of infection. The …

Parasitic protozoa of the phylum Apicomplexa cause a range of human and animal
diseases. Their complex life cycles–often heteroxenous with sexual and asexual phases in …

The physico-chemical processes supporting life's purposeful movement remain essentially
unknown. Self-propelling chiral droplets offer a minimalistic model of swimming cells and, in …

The capacity to migrate is fundamental to multicellular and single-celled life. Apicomplexan
parasites, an ancient protozoan clade that includes malaria parasites (Plasmodium) and …