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Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids
Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …
aroused great interest in medicinal chemists for the development of new drugs or drug …
Biologically active quinoline and quinazoline alkaloids part I
XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …
compounds, have attracted tremendous attention from researchers worldwide since the 19th …
Asymmetric catalysis mediated by synthetic peptides, version 2.0: expansion of scope and mechanisms
Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …
Peptide-based catalysts reach the outer sphere through remote desymmetrization and atroposelectivity
Conspectus Nature's catalytic machinery has provided endless inspiration for chemists.
While the enzymatic ideal has yet to be fully realized, the field has made tremendous strides …
While the enzymatic ideal has yet to be fully realized, the field has made tremendous strides …
4 (3H)-Quinazolinone derivatives: Promising antibacterial drug leads
Emergence of drug resistance has created unmet medical need for the development of new
classes of antibiotics. Discovery of new antibacterial agents with new mode of action …
classes of antibiotics. Discovery of new antibacterial agents with new mode of action …
Organofluorine chemistry: Promising growth areas and challenges
LV Politanskaya, GA Selivanova… - Russian Chemical …, 2019 - iopscience.iop.org
Currently, the chemistry of organofluorine compounds is a leading and rapidly develo**
area of organic chemistry. Fluorine present in a molecule largely determines its specific …
area of organic chemistry. Fluorine present in a molecule largely determines its specific …
Advances in Palladium‐Catalyzed Decarboxylative Cycloadditions of Cyclic Carbonates, Carbamates and Lactones
Y You, Q Li, YP Zhang, JQ Zhao, ZH Wang… - …, 2022 - Wiley Online Library
Palladium‐catalyzed decarboxylative cycloadditions have emerged as highly effective
methods for constructing structurally diverse carbo‐and heterocycles because of the …
methods for constructing structurally diverse carbo‐and heterocycles because of the …
Photo-triggered self-catalyzed fluoroalkylation/cyclization of unactivated alkenes: synthesis of quinazolinones containing the CF 2 R group
J Yang, B Sun, H Ding, PY Huang, XL Tang, RC Shi… - Green …, 2021 - pubs.rsc.org
A novel photo-triggered self-catalyzed fluoroalkylation/cyclization of quinazolinones
containing unactivated alkenes with various fluoroalkyl bromides has been developed. This …
containing unactivated alkenes with various fluoroalkyl bromides has been developed. This …
Ruthenium pincer complex catalyzed efficient synthesis of quinoline, 2-styrylquinoline and quinazoline derivatives via acceptorless dehydrogenative coupling …
The synthesis of N-heterocycles has been considered an emerging area of chemical
research due to their extensive utilization in pharmaceuticals, materials science, and natural …
research due to their extensive utilization in pharmaceuticals, materials science, and natural …
Metal-Free Photoinduced Hydrocyclization of Unactivated Alkenes toward Ring-Fused Quinazolin-4(3H)-ones via Intermolecular Hydrogen Atom Transfer
Z Yang, X Wu, J Zhang, JT Yu, C Pan - Organic Letters, 2023 - ACS Publications
A visible-light-induced hydrocyclization of unactivated alkenes was developed using
3CzClIPN as the photocatalyst to generate substituted α-methyldeoxyvasicinones and α …
3CzClIPN as the photocatalyst to generate substituted α-methyldeoxyvasicinones and α …