The management of neuropsychiatric lupus in the 21st century: still so many unmet needs?

M Govoni, JG Hanly - Rheumatology, 2020 - academic.oup.com
Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

Nervous system disease in systemic lupus erythematosus: current status and future directions

JG Hanly, E Kozora, SD Beyea… - Arthritis & …, 2019 - Wiley Online Library
The American College of Rheumatology's case definitions for 19 neuropsychiatric
syndromes in systemic lupus erythematosus (SLE) constitute a comprehensive classification …

[PDF][PDF] One year in review 2018: systemic lupus erythematosus

M Di Battista, E Marcucci, E Elefante… - Clin Exp …, 2018 - clinexprheumatol.org
Systemic lupus erythematosus (SLE) is a systemic autoimmune condition characterised by a
wide spectrum of clinical manifestations, partly related to the disease itself, but also linked to …

Advances in the diagnosis, pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus

E Moore, MW Huang, C Putterman - Current opinion in …, 2020 - journals.lww.com
Neuropsychiatric involvement of SLE includes a variety of symptoms that impact quality of
life and patient prognosis. There have been recent advances in improving the diagnosis of …

From systemic inflammation to neuroinflammation: the case of neurolupus

M Bendorius, C Po, S Muller… - International journal of …, 2018 - mdpi.com
It took decades to arrive at the general consensus dismissing the notion that the immune
system is independent of the central nervous system. In the case of uncontrolled systemic …

Systemic lupus erythematosus: the search for the ideal biomarker

LA González, MF Ugarte-Gil, GS Alarcón - Lupus, 2021 - journals.sagepub.com
During the last decades, there has been an increased interest in the discovery and
validation of biomarkers that reliably reflect specific aspects of lupus. Although many …

Recent advances in the diagnosis and management of neuropsychiatric lupus

AC Legge, JG Hanly - Nature Reviews Rheumatology, 2024 - nature.com
Neuropsychiatric manifestations of systemic lupus erythematosus (SLE) are common and
frequently associated with a substantial negative impact on health outcomes. The …

Altered white matter microstructure in lupus patients: a diffusion tensor imaging study

J Nystedt, M Nilsson, A Jönsen, P Nilsson… - Arthritis research & …, 2018 - Springer
Background The purpose of this study was to investigate whether white matter
microstructure is altered in patients suffering from systemic lupus erythematosus (SLE), and …

Brain diffusion tensor MRI in systematic lupus erythematosus: a systematic review

BL Costallat, DM Ferreira, AT Lapa, L Rittner… - Autoimmunity …, 2018 - Elsevier
Diffusion tensor imaging (DTI) maps the brain's microstructure by measuring fractional
anisotropy (FA) and mean diffusivity (MD). This systematic review describes brain diffusion …

Longitudinal evaluation of diffusion tensor imaging and cognition in systemic lupus erythematosus

E Kozora, CM Filley, D Erkan, AM Uluğ, A Vo… - Lupus, 2018 - journals.sagepub.com
Objective This pilot study aimed to examine longitudinal changes in brain structure and
function in patients with systemic lupus erythematosus (SLE) using diffusion tensor imaging …