Biomedical applications of biodegradable polymers

BD Ulery, LS Nair, CT Laurencin - Journal of polymer science …, 2011 - Wiley Online Library
Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …

A review on composite liposomal technologies for specialized drug delivery

MS Mufamadi, V Pillay, YE Choonara… - Journal of drug …, 2011 - Wiley Online Library
The combination of liposomes with polymeric scaffolds could revolutionize the current state
of drug delivery technology. Although liposomes have been extensively studied as a …

Injectable graphene oxide/hydrogel-based angiogenic gene delivery system for vasculogenesis and cardiac repair

A Paul, A Hasan, HA Kindi, AK Gaharwar, VTS Rao… - ACS …, 2014 - ACS Publications
The objective of this study was to develop an injectable and biocompatible hydrogel which
can efficiently deliver a nanocomplex of graphene oxide (GO) and vascular endothelial …

Development and characterisation of a collagen nano-hydroxyapatite composite scaffold for bone tissue engineering

GM Cunniffe, GR Dickson, S Partap, KT Stanton… - Journal of Materials …, 2010 - Springer
Bone regeneration requires scaffolds that possess suitable mechanical and biological
properties. This study sought to develop a novel collagen-nHA biocomposite scaffold via two …

Regulated non-viral gene delivery from coaxial electrospun fiber mesh scaffolds

A Saraf, LS Baggett, RM Raphael, FK Kasper… - Journal of Controlled …, 2010 - Elsevier
In an effort to add to the versatility of three-dimensional scaffolds for tissue engineering
applications, recent experimental designs are incorporating biological molecules such as …

Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing

FT Moutos, KA Glass, SA Compton, AK Ross… - Proceedings of the …, 2016 - pnas.org
Biological resurfacing of entire articular surfaces represents an important but challenging
strategy for treatment of cartilage degeneration that occurs in osteoarthritis. Not only does …

Non-viral gene delivery to mesenchymal stem cells: methods, strategies and application in bone tissue engineering and regeneration

JL Santos, D Pandita, J Rodrigues… - Current gene …, 2011 - ingentaconnect.com
Mesenchymal stem cells (MSCs) can be isolated from several tissues in the body, have the
ability to selfrenewal, show immune suppressive properties and are multipotent, being able …

Non-viral gene activated matrices for mesenchymal stem cells based tissue engineering of bone and cartilage

S Raisin, E Belamie, M Morille - Biomaterials, 2016 - Elsevier
Recent regenerative medicine and tissue engineering strategies for bone and cartilage
repair have led to fascinating progress of translation from basic research to clinical …

Collagen: finding a solution for the source

S Browne, DI Zeugolis, A Pandit - Tissue Engineering Part A, 2013 - liebertpub.com
Extracellular matrix (ECM)-based scaffolds, through their inherent bioactivity and molecular
recognition signals, provide the ideal substrate for tissue engineering and regenerative …

Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery

Y Lei, M Rahim, Q Ng, T Segura - Journal of controlled release, 2011 - Elsevier
Local delivery of DNA through a hydrogel scaffold would increase the applicability of gene
therapy in tissue regeneration and cancer therapy. However, the delivery of DNA/cationic …