Novel insights into RB1 mutation
Y Yao, X Gu, X Xu, S Ge, R Jia - Cancer Letters, 2022 - Elsevier
Since the discovery of the retinoblastoma susceptibility gene (RB1) decades ago, RB1 has
been regarded as a prototype tumor suppressor gene providing a paradigm for tumor …
been regarded as a prototype tumor suppressor gene providing a paradigm for tumor …
Global retinoblastoma survival and globe preservation: a systematic review and meta-analysis of associations with socioeconomic and health-care factors
Background Despite advancements in globe-preserving treatments, improvements in
retinoblastoma outcomes are inconsistent across income levels and geographical locations …
retinoblastoma outcomes are inconsistent across income levels and geographical locations …
[HTML][HTML] Global retinoblastoma treatment outcomes: association with national income level
Purpose To compare metastasis-related mortality, local treatment failure and globe salvage
after retinoblastoma (RB) in countries with different national income levels. Design …
after retinoblastoma (RB) in countries with different national income levels. Design …
Single-cell transcriptomics enable the characterization of local extension in retinoblastoma
Y Liu, W Hu, Y **e, J Tang, H Ma, J Li, J Nie… - Communications …, 2024 - nature.com
Retinoblastoma (RB) is the most prevalent ocular tumor of childhood, and its extraocular
invasion significantly increases the risk of metastasis. Nevertheless, a single-cell …
invasion significantly increases the risk of metastasis. Nevertheless, a single-cell …
Three vs 6 cycles of chemotherapy for high-risk retinoblastoma: a randomized clinical trial
Importance Adjuvant therapy is an important and effective treatment for retinoblastoma.
However, there is a lack of head-to-head clinical trials comparing 3 vs 6 cycles of CEV …
However, there is a lack of head-to-head clinical trials comparing 3 vs 6 cycles of CEV …
Highly sensitive detection method of retinoblastoma genetic predisposition and biomarkers
J Le Gall, C Dehainault, C Benoist, A Matet… - The Journal of Molecular …, 2021 - Elsevier
Retinoblastoma is a malignant tumor of the infant retina. Nearly half of patients are
predisposed to retinoblastoma by a germline RB1 pathogenic variant. Nonhereditary …
predisposed to retinoblastoma by a germline RB1 pathogenic variant. Nonhereditary …
Nanoparticle-mediated gene therapy as a novel strategy for the treatment of retinoblastoma
Over the last two decades, nanoparticulate delivery systems have revolutionized cancer
treatment by achieving target-specific delivery, enhanced bioavailability, and improved …
treatment by achieving target-specific delivery, enhanced bioavailability, and improved …
Retinoblastoma outcomes: a global perspective
Retinoblastoma is the most common paediatric eye cancer, and is typically curable through
early diagnosis and protocol-based management. In fact, advanced medical care delivery in …
early diagnosis and protocol-based management. In fact, advanced medical care delivery in …
[HTML][HTML] Establishment and comprehensive characterization of a novel preclinical platform of metastatic retinoblastoma for therapeutic developments
S Zugbi, R Aschero, D Ganiewich… - … & Visual Science, 2023 - tvst.arvojournals.org
Purpose: Although there have been improvements in the management of metastatic
retinoblastoma, most patients do not survive, and all patients suffer from multiple short-and …
retinoblastoma, most patients do not survive, and all patients suffer from multiple short-and …
Neonatal retinoblastoma
FY Lin, MM Chintagumpala - Clinics in Perinatology, 2021 - perinatology.theclinics.com
Retinoblastoma is the most common ocular malignancy of childhood, primarily affecting
children of very young age. In countries with developed medical systems, most cases are …
children of very young age. In countries with developed medical systems, most cases are …