A systematic analysis of all naturally-occurring glycosylated bacterial secondary metabolites
reported in the scientific literature up through early 2013 is presented. This comprehensive …

Glycosyltransferases catalyze glycosidic bond formation using sugar donors containing a
nucleoside phosphate or a lipid phosphate leaving group. Only two structural folds, GT-A …

Glycosylation reactions mainly catalyzed by glycosyltransferases (Gts) occur almost
everywhere in the biosphere, and always play crucial roles in vital processes. In order to …

Natural products have played a prominent role in the history of organic chemistry, and they
continue to be important as drugs, biological probes, and targets of study for synthetic and …

Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

The soil actinomycetes have been important sources of antibiotics, but were nearly
abandoned in recent years in favor of high-throughput target-based screening of chemical …

Herein, the catalytic promiscuity of TcCGT1, a new C‐glycosyltransferase (CGT) from the
medicinal plant Trollius chinensis is explored. TcCGT1 could efficiently and regio …

Many biologically active small‐molecule natural products produced by microorganisms
derive their activities from sugar substituents. Changing the structures of these sugars can …

Glycosylation is a chemical transformation that is centrally important in all glycoscience and
related technologies. Catalysts offering good control over reactivity and selectivity in …

Abstract Sucrose synthase (SuSy, EC 2.4. 1.13) is a glycosyltransferase (GT) long known
from plants and more recently discovered in bacteria. The enzyme catalyzes the reversible …