[HTML][HTML] Enhancing translation: A need to leverage complex preclinical models of addictive drugs to accelerate substance use treatment options
C Corley, A Craig, S Sadek, JA Marusich… - Pharmacology …, 2024 - Elsevier
Preclinical models of addictive drugs have been developed for decades to model aspects of
the clinical experience in substance use disorders (SUDs). These include passive exposure …
the clinical experience in substance use disorders (SUDs). These include passive exposure …
Xylazine exacerbates fentanyl-induced respiratory depression and bradycardia
Fatal opioid overdoses in the United States have nearly tripled during the past decade, with
greater than 92% involving a synthetic opioid like fentanyl. Fentanyl potently activates the μ …
greater than 92% involving a synthetic opioid like fentanyl. Fentanyl potently activates the μ …
Xylazine does not enhance fentanyl reinforcement in rats: A behavioral economic analysis
The adulteration of illicit fentanyl with the alpha-2 agonist xylazine has been designated an
emerging public health threat. The clinical rationale for combining fentanyl with xylazine is …
emerging public health threat. The clinical rationale for combining fentanyl with xylazine is …
Effects of xylazine on naloxone-precipitated fentanyl withdrawal in male and female rats
HN Carlson, AG Spera, MA Smith - Drug and Alcohol Dependence, 2024 - Elsevier
Purpose The combination of fentanyl and xylazine (ie,“tranq-dope”) was recently declared
an emerging national health threat in the United States. Given the recency of this …
an emerging national health threat in the United States. Given the recency of this …
Gambaran Hematologi dari Pemberian Anestesi Kombinasi Ketamin-**lazin dan Ketamin-Diazepam pada Pelaksanaan Kastrasi An**g.
T Utami, TC Tophianong… - Jurnal Kajian …, 2024 - search.ebscohost.com
Carrying out castration on dogs requires anesthesia to prevent movement and relieve pain
during the operation. The aim of this study was to evaluate the effects of administering two …
during the operation. The aim of this study was to evaluate the effects of administering two …