Eosinophils are important effector cells and therapeutic targets in allergic diseases.
Emerging data indicate that eosinophils infiltrate a variety of solid tumor types and have …

Despite being an integral part of the immune response in the tumor microenvironment
(TME), few studies have mechanistically elucidated eosinophil functions in cancer …

Eosinophils are bone marrow-derived granulocytes that are traditionally associated with
type 2 immune responses, such as those that occur during parasite infections and allergy …

Chimeric antigen receptor (CAR) T-cell therapies have achieved remarkable success in the
treatment of haematological malignancies. Over the past 9 years, the use of CAR T-cell …

Neurodegenerative diseases (NDDs) affect more than 50 million people worldwide, posing
a significant global health challenge as well as a high socioeconomic burden. With aging …

There is a need for better predictive models of the human immune system to evaluate safety
and efficacy of immunomodulatory drugs and biologics for successful product development …

In recent years, great strides have been made toward the development of immune cell‐
based therapies in the treatment of refractory malignancies. Primary T cells and NK cells …

Human pluripotent stem cells (hPSCs) have been suggested as a potential source for the
production of blood cells for clinical application. In two decades, almost all types of blood …

The role of eosinophils, a cell type involved in the immune response to parasitic infections
and allergies, has been investigated in different cancer types, in both tumor tissue and at the …

Cancer cells circumvent immune surveillance via diverse strategies. In accordance, a large
number of complex studies of the immune system focusing on tumor cell recognition have …