Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Glycerol-based ether lipids including ether phospholipids form a specialized branch of lipids
that in mammals require peroxisomes for their biosynthesis. They are major components of …

Metabolic alteration for adaptation of the local environment has been recognized as a
hallmark of cancer. GNPAT dysregulation has been implicated in hepatocellular carcinoma …

The emerging diverse roles of ether (phospho) lipids in nervous system development and
function in health and disease are currently attracting growing interest. Plasmalogens, a …

The lipidome is currently understudied but fundamental to life. Within the brain, little is
known about cell-type lipid heterogeneity, and even less is known about cell-to-cell lipid …

Structural properties of plasmenyl-glycerophospholipids (plasmalogens) have been scarcely
studied for plasmalogens with long polyunsaturated fatty acid (PUFA) chains, despite of their …

Ether-lipids (EL) are specific lipids bearing a characteristic sn-1 ether bond. Depending on
the ether or vinyl-ether nature of this bond, they are present as alkyl-or alkenyl-EL …

Plasmalogens, the most prominent ether (phospho) lipids in mammals, are structural
components of most cellular membranes. Due to their physicochemical properties and …

Plasmalogens are a specific type of glycerophospholipid found in especially high levels in
neuronal membranes. Decreased blood and brain levels of docosahexaenoic acid (DHA) …

The synaptic cleft of the neuromuscular junction (NMJ) consists of a highly specialized
extracellular matrix (ECM) involved in synapse maturation, in the juxtaposition of pre-to post …