The mutational landscape of colorectal cancer (CRC) does not enable predictions to be
made about the survival of patients or their response to therapy. Instead, studying the …

Short-chain fatty acids (SCFAs), mainly including acetate, propionate, and butyrate, are
metabolites produced during the bacterial fermentation of dietary fiber in the intestinal tract …

The gut microbiota plays a role in many human diseases, but high-throughput sequence
analysis does not provide a straightforward path for defining healthy microbial communities …

Inflammation predisposes to the development of cancer and promotes all stages of
tumorigenesis. Cancer cells, as well as surrounding stromal and inflammatory cells, engage …

Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

An increasing number of studies have revealed that the progression of colorectal cancer
(CRC) is related to gut microbiome composition. Under normal conditions, the gut …

Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3) expression has been
a trending topic in recent years due to its differential expression in a wide range of …

The relationship between chronic inflammation and neoplastic diseases is not fully
understood. The inflammatory microenvironment of a tumor is an intricate network that …

Inflammatory bowel disease (IBD)-related colorectal cancer (CRC) is responsible for
approximately 2% of the annual mortality from CRC overall, but 10–15% of the annual …