Emerging carbon-supported single-atom catalysts for biomedical applications

G Liao, L Zhang, C Li, SY Liu, B Fang, H Yang - Matter, 2022 - cell.com
Carbon-supported single-atom catalysts (SACs) are very promising for biomedical
applications due to their unique superiorities, including uniform size in nanoscale, ease of …

Single-atom nanozymes with peroxidase-like activity: A review

EM Hamed, V Rai, SFY Li - Chemosphere, 2024 - Elsevier
Single-atom nanozymes (SANs) are nanomaterials-based nanozymes with atomically
dispersed enzyme-like active sites. SANs offer improved as well as tunable catalytic activity …

Employing noble metal–porphyrins to engineer robust and highly active single‐atom nanozymes for targeted catalytic therapy in nasopharyngeal carcinoma

D Wang, J Wang, XJ Gao, H Ding, M Yang… - Advanced …, 2024 - Wiley Online Library
Single‐atom nanozymes (SANzymes) emerge as promising alternatives to conventional
enzymes. However, chemical instability limits their application. Here, a systematic synthesis …

Nanomaterial-based regulation of redox metabolism for enhancing cancer therapy

X Jia, Y Wang, Y Qiao, X Jiang, J Li - Chemical Society Reviews, 2024 - pubs.rsc.org
Altered redox metabolism is one of the hallmarks of tumor cells, which not only contributes to
tumor proliferation, metastasis, and immune evasion, but also has great relevance to …

Concave single-atom Co nanozymes with densely edge-hosted active sites for highly sensitive immunoassay

P Xu, C Tao, Y Jiang, S Chu, K Song, Y Lu - Chemical Engineering Journal, 2024 - Elsevier
Regulating the geometric and electronic structures of single-atom catalysts could promote
the potential to improve their enzyme-like catalytic performance. Herein, we demonstrate …

Highly active single-atom nanozymes with high-loading iridium for sensitive detection of pesticides

Y Wang, L Yin, G Qu, CH Leung, L Han… - Analytical …, 2023 - ACS Publications
Single-atom nanozymes (SAzymes) are novel mimic-enzyme materials with atomically
doped active sites. They play a pivotal role in the field of nanozymes because of their …

Heteronuclear dual-metal atom catalysts for nanocatalytic tumor therapy

J Han, J Guan - Chinese Journal of Catalysis, 2023 - Elsevier
Due to excellent catalytic activity and high atomic utilization rate, single atom catalysts
(SACs) have become a rising star in the field of nanocatalytic medicine. Heteronuclear dual …

Glutathione-responsive and-exhausting metal nanomedicines for robust synergistic cancer therapy

P Liu, L Hao, M Liu, S Hu - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Due to their rapid and uncontrolled proliferation, cancer cells are characterized by
overexpression of glutathione (GSH), which impairs reactive oxygen species (ROS)-based …

[HTML][HTML] Emerging prospects of nanozymes for antibacterial and anticancer applications

N Chakraborty, S Gandhi, R Verma, I Roy - Biomedicines, 2022 - mdpi.com
The ability of some nanoparticles to mimic the activity of certain enzymes paves the way for
several attractive biomedical applications which bolster the already impressive arsenal of …

Targeting tumor microenvironment by metal peroxide nanoparticles in cancer therapy

SN Mbugua - Bioinorganic Chemistry and Applications, 2022 - Wiley Online Library
Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low
acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These …