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Mesenchymal stem/stromal cells in cancer therapy
T Lan, M Luo, X Wei - Journal of Hematology & Oncology, 2021 - Springer
The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …
marrow in 1976, have been identified in nearly all tissues of human body now. The …
Therapeutic potential of mesenchymal stem cells for cancer therapy
A Hmadcha, A Martin-Montalvo, BR Gauthier… - … in bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for
regenerative medicine. A large number of studies have shown the beneficial effects of MSC …
regenerative medicine. A large number of studies have shown the beneficial effects of MSC …
Ethical and safety issues of stem cell-based therapy
V Volarevic, BS Markovic, M Gazdic… - … journal of medical …, 2018 - pmc.ncbi.nlm.nih.gov
Results obtained from completed and on-going clinical studies indicate huge therapeutic
potential of stem cell-based therapy in the treatment of degenerative, autoimmune and …
potential of stem cell-based therapy in the treatment of degenerative, autoimmune and …
Mesenchymal stem cells: key players in cancer progression
Tumour progression is dependent on the interaction between tumour cells and cells of the
surrounding microenvironment. The tumour is a dynamic milieu consisting of various cell …
surrounding microenvironment. The tumour is a dynamic milieu consisting of various cell …
MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in …
Background Human mesenchymal stem cells (MSCs) have been shown to be involved in
the formation and modulation of tumor stroma and in interacting with tumor cells, partly …
the formation and modulation of tumor stroma and in interacting with tumor cells, partly …
The role of TNF-α in the fate regulation and functional reprogramming of mesenchymal stem cells in an inflammatory microenvironment
W Li, Q Liu, J Shi, X Xu, J Xu - Frontiers in immunology, 2023 - frontiersin.org
Mesenchymal stem cells (MSCs) are pluripotent stem cells with multidirectional
differentiation potential and strong immunomodulatory capacity. MSCs have been widely …
differentiation potential and strong immunomodulatory capacity. MSCs have been widely …
Mesenchymal stem cell-released oncolytic virus: an innovative strategy for cancer treatment
N Ghasemi Darestani, AI Gilmanova… - Cell Communication and …, 2023 - Springer
Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …
damage to normal cells in the process. Because of their specific features, such as, the ability …
Exosomes derived from mesenchymal stem cells suppress angiogenesis by down-regulating VEGF expression in breast cancer cells
JK Lee, SR Park, BK Jung, YK Jeon, YS Lee, MK Kim… - PloS one, 2013 - journals.plos.org
Exosomes are small membrane vesicles released by a variety of cell types. Exosomes
contain genetic materials, such as mRNAs and microRNAs (miRNAs), implying that they …
contain genetic materials, such as mRNAs and microRNAs (miRNAs), implying that they …
A new approach for loading anticancer drugs into mesenchymal stem cell-derived exosome mimetics for cancer therapy
Exosomes derived from mesenchymal stem cells (MSCs) have been evaluated for their
potential to be used as drug delivery vehicles. Synthetically personalized exosome mimetics …
potential to be used as drug delivery vehicles. Synthetically personalized exosome mimetics …
Mesenchymal stem cells in health and disease
Mesenchymal stem cells (MSCs) are a heterogeneous subset of stromal stem cells that can
be isolated from many adult tissues. They can differentiate into cells of the mesodermal …
be isolated from many adult tissues. They can differentiate into cells of the mesodermal …