Immune regulatory networks coordinated by glycans and glycan-binding proteins in autoimmunity and infection
The immune system is coordinated by an intricate network of stimulatory and inhibitory
circuits that regulate host responses against endogenous and exogenous insults. Disruption …
circuits that regulate host responses against endogenous and exogenous insults. Disruption …
[HTML][HTML] Gram-positive bacterial cell envelopes: The impact on the activity of antimicrobial peptides
N Malanovic, K Lohner - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
A number of cationic antimicrobial peptides, effectors of innate immunity, are supposed to
act at the cytoplasmic membrane leading to permeabilization and eventually membrane …
act at the cytoplasmic membrane leading to permeabilization and eventually membrane …
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2
Q Lu, J Liu, S Zhao, MFG Castro, M Laurent-Rolle… - Immunity, 2021 - cell.com
Despite mounting evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) engagement with immune cells, most express little, if any, of the canonical receptor of …
2) engagement with immune cells, most express little, if any, of the canonical receptor of …
Antimicrobial peptides targeting gram-positive bacteria
N Malanovic, K Lohner - Pharmaceuticals, 2016 - mdpi.com
Antimicrobial peptides (AMPs) have remarkably different structures as well as biological
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …
Exosome mimetics: a novel class of drug delivery systems
SAA Kooijmans, P Vader… - International journal …, 2012 - Taylor & Francis
The identification of extracellular phospholipid vesicles as conveyors of cellular information
has created excitement in the field of drug delivery. Biological therapeutics, including short …
has created excitement in the field of drug delivery. Biological therapeutics, including short …
Resveratrol and immune cells: a link to improve human health
The use of polyphenols as adjuvants in lowering risk factors for various debilitating diseases
has been investigated in recent years due to their possible antioxidant action. Polyphenols …
has been investigated in recent years due to their possible antioxidant action. Polyphenols …
Natural and synthetic saponins as vaccine adjuvants
P Wang - Vaccines, 2021 - mdpi.com
Saponin adjuvants have been extensively studied for their use in veterinary and human
vaccines. Among them, QS-21 stands out owing to its unique profile of immunostimulating …
vaccines. Among them, QS-21 stands out owing to its unique profile of immunostimulating …
Adaptive immune activation: glycosylation does matter
MA Wolfert, GJ Boons - Nature chemical biology, 2013 - nature.com
Major histocompatibility complex (MHC) class I and II are glycoproteins that can present
antigenic peptides at the cell surface for recognition and activation of circulating T …
antigenic peptides at the cell surface for recognition and activation of circulating T …
C-type lectins: their network and roles in pathogen recognition and immunity
S Mayer, MK Raulf, B Lepenies - Histochemistry and cell biology, 2017 - Springer
C-type lectins (CTLs) represent the most complex family of animal/human lectins that
comprises 17 different groups. During evolution, CTLs have developed by diversification to …
comprises 17 different groups. During evolution, CTLs have developed by diversification to …
Glycopolymer probes of signal transduction
LL Kiessling, JC Grim - Chemical Society Reviews, 2013 - pubs.rsc.org
Glycans are key participants in biological processes ranging from reproduction to cellular
communication to infection. Revealing glycan roles and the underlying molecular …
communication to infection. Revealing glycan roles and the underlying molecular …