Computational models of the basal ganglia: from robots to membranes
With the rapid accumulation of neuroscientific data comes a pressing need to develop
models that can explain the computational processes performed by the basal ganglia …
models that can explain the computational processes performed by the basal ganglia …
Short-term and long-term plasticity at corticostriatal synapses: implications for learning and memory
The striatum is the major division of the basal ganglia, representing the input station of the
circuit and arguably the principal site within the basal ganglia where information processing …
circuit and arguably the principal site within the basal ganglia where information processing …
Transient, consequential increases in extracellular potassium ions accompany channelrhodopsin2 excitation
Summary Channelrhodopsin2 (ChR2) optogenetic excitation is widely used to study
neurons, astrocytes, and circuits. Using complementary approaches in situ and in vivo, we …
neurons, astrocytes, and circuits. Using complementary approaches in situ and in vivo, we …
Pallidostriatal projections promote β oscillations in a dopamine-depleted biophysical network model
VL Corbit, TC Whalen, KT Zitelli, SY Crilly… - Journal of …, 2016 - jneurosci.org
In the basal ganglia, focused rhythmicity is an important feature of network activity at certain
stages of motor processing. In disease, however, the basal ganglia develop amplified …
stages of motor processing. In disease, however, the basal ganglia develop amplified …
A new framework for cortico-striatal plasticity: behavioural theory meets in vitro data at the reinforcement-action interface
Operant learning requires that reinforcement signals interact with action representations at a
suitable neural interface. Much evidence suggests that this occurs when phasic dopamine …
suitable neural interface. Much evidence suggests that this occurs when phasic dopamine …
NMDA/AMPA ratio impacts state transitions and entrainment to oscillations in a computational model of the nucleus accumbens medium spiny projection neuron
We describe a computational model of the principal cell in the nucleus accumbens (NAcb),
the medium spiny projection (MSP) neuron. The model neuron, constructed in NEURON …
the medium spiny projection (MSP) neuron. The model neuron, constructed in NEURON …
Homeostatic plasticity of striatal neurons intrinsic excitability following dopamine depletion
K Azdad, M Chàvez, PD Bischop, P Wetzelaer… - PloS one, 2009 - journals.plos.org
The striatum is the major input structure of basal ganglia and is involved in adaptive control
of behaviour through the selection of relevant informations. Dopaminergic neurons that …
of behaviour through the selection of relevant informations. Dopaminergic neurons that …
Corticostriatal plasticity: life after the depression
S Mahon, JM Deniau, S Charpier - Trends in neurosciences, 2004 - cell.com
Experience-dependent changes in corticostriatal transmission efficacy are likely to support
the role of the striatum in reinforcement-based motor learning. Whereas long-term …
the role of the striatum in reinforcement-based motor learning. Whereas long-term …
Capturing dopaminergic modulation and bimodal membrane behaviour of striatal medium spiny neurons in accurate, reduced models
Loss of dopamine from the striatum can cause both profound motor deficits, as in
Parkinsons's disease, and disrupt learning. Yet the effect of dopamine on striatal neurons …
Parkinsons's disease, and disrupt learning. Yet the effect of dopamine on striatal neurons …
Contrast enhancement: a physiological effect of striatal dopamine?
SM Nicola, F Woodward Hopf, GO Hjelmstad - Cell and tissue research, 2004 - Springer
Dopamine functions as an important neuromodulator in the dorsal striatum and ventral
striatum/nucleus accumbens. Evidence is accumulating for the idea that striatal neurons …
striatum/nucleus accumbens. Evidence is accumulating for the idea that striatal neurons …