Natural inhibitors of cholinesterases: chemistry, structure–activity and methods of their analysis

N Smyrska-Wieleba, T Mroczek - International Journal of Molecular …, 2023 - mdpi.com
This article aims to provide an updated description and comparison of the data currently
available in the literature (from the last 15 years) on the studied natural inhibitors of …

Non-alkaloid cholinesterase inhibitory compounds from natural sources

AN Tamfu, S Kucukaydin, B Yeskaliyeva, M Ozturk… - Molecules, 2021 - mdpi.com
Alzheimer's disease (AD) is a severe neurodegenerative disorder of different brain regions
accompanied by distresses and affecting more than 25 million people in the world. This …

In vitro enzyme inhibitory properties, antioxidant activities, and phytochemical profile of Potentilla thuringiaca

DM Grochowski, S Uysal, A Aktumsek, S Granica… - Phytochemistry …, 2017 - Elsevier
The genus Potentilla is interesting for the pharmaceutical field due to its valuable medicinal
properties, which have been observed in complementary and alternative medicine. In recent …

Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia

A Knežević, M Stajić, I Sofrenić, T Stanojković… - PloS one, 2018 - journals.plos.org
In a last few decades mushrooms are increasingly attracting attention as functional food and
sources of biologically active compounds. Several Trametes species have been used for …

Plant terpenoids as the promising source of cholinesterase inhibitors for anti-AD therapy

S Lai Shi Min, SY Liew, NJY Chear, BH Goh, WN Tan… - Biology, 2022 - mdpi.com
Simple Summary Plant-derived terpenes have been a research interest in the recent years,
as they are believed to possess the ability to function as a cholinesterase inhibitor. As the …

Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations

M Locatelli, G Zengin, A Uysal, S Carradori… - Journal of enzyme …, 2017 - Taylor & Francis
The current study was carried out to evaluate multicomponent pattern, biological and
enzymatic activities of seven Asphodeline taxa root extracts as useful ingredients, due to the …

Antioxidant and anti-acetylcholinesterase potential of artichoke phenolic compounds

NM Abd El-Aziz, OME Awad, MG Shehata… - Food Bioscience, 2021 - Elsevier
The present study focused on the biochemical evaluation of artichoke extract, furthermore, in
vitro and in silico evaluation its potential for inhibition of acetylcholinesterase activity. The …

Anticholinesterase Activity of Eight Medicinal Plant Species: In Vitro and In Silico Studies in the Search for Therapeutic Agents against Alzheimer's Disease

MJ Uddin, D Russo, MM Rahman… - Evidence‐Based …, 2021 - Wiley Online Library
Many Bangladeshi medicinal plants have been used to treat Alzheimer's disease and other
neurodegenerative diseases. In the present study, the anticholinesterase effects of eight …

In vitro antioxidant and enzyme inhibitory properties of Rubus caesius L

DM Grochowski, S Uysal, G Zengin… - International journal of …, 2019 - Taylor & Francis
ABSTRACT The genus Rubus (Rosaceae) has great potential for and a history of use as
natural agents in several traditional folk remedies. Based on this concept, this study focused …

Natural indole butyrylcholinesterase inhibitors from Nauclea officinalis

SY Liew, KY Khaw, V Murugaiyah, CY Looi, YL Wong… - Phytomedicine, 2015 - Elsevier
Nine monoterpenoid indole alkaloids; naucletine (1), angustidine (2), nauclefine (3),
angustine (4), naucline (5), angustoline (6), harmane (7), 3, 14-dihydroangustoline (8) …