Epilepsy and brain network hubs

J Royer, BC Bernhardt, S Larivière, E Gleichgerrcht… - …, 2022 - Wiley Online Library
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …

Neurobehavioural comorbidities of epilepsy: towards a network-based precision taxonomy

BP Hermann, AF Struck, RM Busch, A Reyes… - Nature Reviews …, 2021 - nature.com
Cognitive and behavioural comorbidities are prevalent in childhood and adult epilepsies
and impose a substantial human and economic burden. Over the past century, the classic …

Map** lesion-related epilepsy to a human brain network

FL Schaper, J Nordberg, AL Cohen, C Lin, J Hsu… - JAMA …, 2023 - jamanetwork.com
Importance It remains unclear why lesions in some locations cause epilepsy while others do
not. Identifying the brain regions or networks associated with epilepsy by map** these …

Identification of different MRI atrophy progression trajectories in epilepsy by subtype and stage inference

F **ao, L Caciagli, B Wandschneider, D Sone… - Brain, 2023 - academic.oup.com
Artificial intelligence (AI)-based tools are widely employed, but their use for diagnosis and
prognosis of neurological disorders is still evolving. Here we analyse a cross-sectional …

Uncovering the biological basis of control energy: Structural and metabolic correlates of energy inefficiency in temporal lobe epilepsy

X He, L Caciagli, L Parkes, J Stiso, TM Karrer… - Science …, 2022 - science.org
Network control theory is increasingly used to profile the brain's energy landscape via
simulations of neural dynamics. This approach estimates the control energy required to …

The ictal signature of thalamus and basal ganglia in focal epilepsy: a SEEG study

F Pizzo, N Roehri, B Giusiano, S Lagarde, R Carron… - Neurology, 2021 - AAN Enterprises
Objective To determine the involvement of subcortical regions in human epilepsy by
analyzing direct recordings from these regions during epileptic seizures using stereo-EEG …

Identification of four biotypes in temporal lobe epilepsy via machine learning on brain images

Y Jiang, W Li, J Li, X Li, H Zhang, X Sima, L Li… - Nature …, 2024 - nature.com
Artificial intelligence provides an opportunity to try to redefine disease subtypes based on
similar pathobiology. Using a machine-learning algorithm (Subtype and Stage Inference) …

Personalizing deep brain stimulation using advanced imaging sequences

C Neudorfer, D Kroneberg, B Al‐Fatly… - Annals of …, 2022 - Wiley Online Library
Objective With a growing appreciation for interindividual anatomical variability and patient‐
specific brain connectivity, advanced imaging sequences offer the opportunity to directly …

Thalamus and focal to bilateral seizures: A multiscale cognitive imaging study

L Caciagli, LA Allen, X He, K Trimmel, SB Vos… - Neurology, 2020 - AAN Enterprises
Objective To investigate the functional correlates of recurrent secondarily generalized
seizures in temporal lobe epilepsy (TLE) using task-based fMRI as a framework to test for …

Focal to bilateral tonic–clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy

N Sinha, N Peternell, GM Schroeder, J de Tisi… - …, 2021 - Wiley Online Library
Objective Our objective was to identify whether the whole‐brain structural network
alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic–clonic …