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Leishmaniasis in humans: drug or vaccine therapy?
Leishmania is an obligate intracellular pathogen that invades phagocytic host cells.
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …
[HTML][HTML] Status of vaccine research and development of vaccines for leishmaniasis
PM Gillespie, CM Beaumier, U Strych, T Hayward… - Vaccine, 2016 - Elsevier
A number of leishmaniasis vaccine candidates are at various stages of pre-clinical and
clinical development. Leishmaniasis is a vector-borne neglected tropical disease (NTD) …
clinical development. Leishmaniasis is a vector-borne neglected tropical disease (NTD) …
Current visceral leishmaniasis research: a research review to inspire future study
Visceral leishmaniasis (VL), one of the deadliest parasitic diseases in the world, causes
more than 50,000 human deaths each year and afflicts millions of people throughout South …
more than 50,000 human deaths each year and afflicts millions of people throughout South …
Leishmania vaccines entered in clinical trials: a review of literature
Leishmaniasis is considered as a zoonotic infection and neglected tropical disease.
Leishmania treatment is not totally successful and imposes high expenditures, especially in …
Leishmania treatment is not totally successful and imposes high expenditures, especially in …
A sand fly salivary protein vaccine shows efficacy against vector-transmitted cutaneous leishmaniasis in nonhuman primates
F Oliveira, E Rowton, H Aslan, R Gomes… - Science translational …, 2015 - science.org
Currently, there are no commercially available human vaccines against leishmaniasis. In
rodents, cellular immunity to salivary proteins of sand fly vectors is associated to protection …
rodents, cellular immunity to salivary proteins of sand fly vectors is associated to protection …
Leishmaniasis and various immunotherapeutic approaches
Leishmaniasis is a vector-borne infectious disease caused by multiple Leishmania (L.)
species with diverse clinical manifestations. There is currently no vaccine against any form …
species with diverse clinical manifestations. There is currently no vaccine against any form …
Nanotechnology-based strategies in parasitic disease management: from prevention to diagnosis and treatment
Parasitic infections are a major global health issue causing significant mortality and
morbidity. Despite substantial advances in the diagnostics and treatment of these diseases …
morbidity. Despite substantial advances in the diagnostics and treatment of these diseases …
Immunotherapy and immunochemotherapy in combating visceral leishmaniasis
Visceral leishmaniasis (VL), a vector-borne disease, is caused by an obligate
intramacrophage, kinetoplastid protozoan parasite of the genus Leishmania. Globally, VL is …
intramacrophage, kinetoplastid protozoan parasite of the genus Leishmania. Globally, VL is …
In-silico design of an immunoinformatics based multi-epitope vaccine against Leishmania donovani
Abstract Background Visceral Leishmaniasis (VL) is a fatal vector-borne parasitic disorder
occurring mainly in tropical and subtropical regions. VL falls under the category of neglected …
occurring mainly in tropical and subtropical regions. VL falls under the category of neglected …
[HTML][HTML] A large-scale field randomized trial demonstrates safety and efficacy of the vaccine LetiFend® against canine leishmaniosis
JF Cotrina, V Iniesta, I Monroy, V Baz, C Hugnet… - Vaccine, 2018 - Elsevier
Canine leishmaniosis is a zoonotic disease caused by Leishmania infantum. Extensive
research is currently ongoing to develop safe and effective vaccines to protect from disease …
research is currently ongoing to develop safe and effective vaccines to protect from disease …