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Caffeine and Parkinson's disease: multiple benefits and emerging mechanisms
X Ren, JF Chen - Frontiers in Neuroscience, 2020 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disorder,
characterized by dopaminergic neurodegeneration, motor impairment and non-motor …
characterized by dopaminergic neurodegeneration, motor impairment and non-motor …
Neurotoxicity of MDMA: Main effects and mechanisms
G Costa, K Gołembiowska - Experimental neurology, 2022 - Elsevier
Preclinical and clinical studies indicate that 3, 4-methylenedioxymethamphetamine
(MDMA;'ecstasy'), in addition to having abuse potential, may elicit acute and persistent …
(MDMA;'ecstasy'), in addition to having abuse potential, may elicit acute and persistent …
[HTML][HTML] Neurodegenerative diseases: Can caffeine be a powerful ally to weaken neuroinflammation?
In recent years, there has been considerable research showing that coffee consumption
seems to be beneficial to human health, as it contains a mixture of different bioactive …
seems to be beneficial to human health, as it contains a mixture of different bioactive …
[HTML][HTML] Do caffeine and more selective adenosine A2A receptor antagonists protect against dopaminergic neurodegeneration in Parkinson's disease?
JF Chen, MA Schwarzschild - Parkinsonism & related disorders, 2020 - Elsevier
The adenosine A 2A receptor is a major target of caffeine, the most widely used
psychoactive substance worldwide. Large epidemiological studies have long shown …
psychoactive substance worldwide. Large epidemiological studies have long shown …
[HTML][HTML] Withania somnifera influences MDMA-induced hyperthermic, cognitive, neurotoxic and neuroinflammatory effects in mice
Withania somnifera (WS) is utilized in Ayurvedic medicine owing to its central and peripheral
beneficial properties. Several studies have accrued indicating that the recreational …
beneficial properties. Several studies have accrued indicating that the recreational …
The impact of psychostimulants on central and peripheral neuro-immune regulation: a sco** review of cytokine profiles and their implications for addiction
J Bravo, C Magalhães, EB Andrade… - Frontiers in Cellular …, 2023 - frontiersin.org
It is now well-accepted that psychostimulants act on glial cells causing neuroinflammation
and adding to the neurotoxic effects of such substances. Neuroinflammation can be …
and adding to the neurotoxic effects of such substances. Neuroinflammation can be …
Brain dysfunctions and neurotoxicity induced by psychostimulants in experimental models and humans: an overview of recent findings
Preclinical and clinical studies indicate that psychostimulants, in addition to having abuse
potential, may elicit brain dysfunctions and/or neurotoxic effects. Central toxicity induced by …
potential, may elicit brain dysfunctions and/or neurotoxic effects. Central toxicity induced by …
Caffeine-based food supplements and beverages: Trends of consumption for performance purposes and safety concerns
SMF Bessada, RC Alves, MBPP Oliveira - Food Research International, 2018 - Elsevier
Nowadays, daily food supplementation regarding the improvement of physical and mental
performance is a growing trend in sport practitioners, young students and active people …
performance is a growing trend in sport practitioners, young students and active people …
Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies
G Costa, MA De Luca, G Piras, J Marongiu… - Neural regeneration …, 2020 - journals.lww.com
Preclinical and clinical studies indicate that synthetic psychoactive substances, in addition to
having abuse potential, may elicit toxic effects of varying severity at the peripheral and …
having abuse potential, may elicit toxic effects of varying severity at the peripheral and …
Neuroinflammation and L-dopa-induced abnormal involuntary movements in 6-hydroxydopamine-lesioned rat model of Parkinson's disease are counteracted by …
Several lines of evidence have strongly implicated neuroinflammation in Parkinson's
disease (PD) progression and l-dopa-induced dyskinesia. The present study investigated …
disease (PD) progression and l-dopa-induced dyskinesia. The present study investigated …