The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics
Skyline is a freely available, open‐source Windows client application for accelerating
targeted proteomics experimentation, with an emphasis on the proteomics and mass …
targeted proteomics experimentation, with an emphasis on the proteomics and mass …
Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future
The rumen is a complex ecosystem composed of anaerobic bacteria, protozoa, fungi,
methanogenic archaea and phages. These microbes interact closely to breakdown plant …
methanogenic archaea and phages. These microbes interact closely to breakdown plant …
Single-cell spatial transcriptome reveals cell-type organization in the macaque cortex
Elucidating the cellular organization of the cerebral cortex is critical for understanding brain
structure and function. Using large-scale single-nucleus RNA sequencing and spatial …
structure and function. Using large-scale single-nucleus RNA sequencing and spatial …
Recovering gene interactions from single-cell data using data diffusion
Single-cell RNA sequencing technologies suffer from many sources of technical noise,
including under-sampling of mRNA molecules, often termed" dropout," which can severely …
including under-sampling of mRNA molecules, often termed" dropout," which can severely …
A practical guide to linking brain-wide gene expression and neuroimaging data
The recent availability of comprehensive, brain-wide gene expression atlases such as the
Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …
Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …
Chemotherapy resistance in advanced ovarian cancer patients
Ovarian cancer is the seventh most common gynaecologic malignancy seen in women.
Majority of the patients with ovarian cancer are diagnosed at the advanced stage making …
Majority of the patients with ovarian cancer are diagnosed at the advanced stage making …
Positive controls in adults and children support that very few, if any, new neurons are born in the adult human hippocampus
Adult hippocampal neurogenesis was originally discovered in rodents. Subsequent studies
identified the adult neural stem cells and found important links between adult neurogenesis …
identified the adult neural stem cells and found important links between adult neurogenesis …
Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system
Differential mRNA expression studies implicitly assume that changes in mRNA expression
have biological meaning, most likely mediated by corresponding changes in protein levels …
have biological meaning, most likely mediated by corresponding changes in protein levels …
Scaling by shrinking: empowering single-cell'omics' with microfluidic devices
Recent advances in cellular profiling have demonstrated substantial heterogeneity in the
behaviour of cells once deemed'identical', challenging fundamental notions of …
behaviour of cells once deemed'identical', challenging fundamental notions of …
[HTML][HTML] Integrative multi-omics approaches in cancer research: from biological networks to clinical subtypes
YJ Heo, C Hwa, GH Lee, JM Park, JY An - Molecules and cells, 2021 - Elsevier
Multi-omics approaches are novel frameworks that integrate multiple omics datasets
generated from the same patients to better understand the molecular and clinical features of …
generated from the same patients to better understand the molecular and clinical features of …