The Glial cell line-derived neurotrophic Family Ligands (GFL) are soluble neurotrophic
factors that are required for development of multiple human tissues, but which are also …

Animals display selective escape behaviors when faced with environmental threats.
Selection of the appropriate response by the underlying neuronal network is key to …

Highlights•Compare and contrast fibroblast focal adhesions with growth cone point contact
adhesions.•Compare and contrast invadosomes of invasive cancer cells with analogous …

During neuronal pruning, phagocytes engulf shed cellular debris to avoid inflammation and
maintain tissue homeostasis. How phagocytic receptors recognize degenerating neurites …

The formation of neuronal dendrite branches is fundamental for the wiring and function of
the nervous system. Indeed, dendrite branching enhances the coverage of the neuron's …

Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect from cancer
treatment with no known method for prevention or cure in clinics. CIPN often affects …

A spinocerebellar ataxia type 5 (SCA5) L253P mutation in the actin-binding domain (ABD) of
β-III-spectrin causes high-affinity actin binding and decreased thermal stability in vitro. Here …

Neurons sometimes completely fill available space in their receptive fields with evenly
spaced dendrites to uniformly sample sensory or synaptic information. The mechanisms that …

Precise patterning of dendritic arbors is critical for the wiring and function of neural circuits.
Dendrite-extracellular matrix (ECM) adhesion ensures that the dendrites of Drosophila …

Microtubules are essential for neuronal structure and function. Axonal and dendritic
microtubules are enriched in post-translational modifications that impact microtubule …