The current active–latent paradigm of tuberculosis largely neglects the documented
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …

Tuberculosis (TB) is a leading cause of morbidity and mortality from a single infectious
agent, despite being preventable and curable. Early and accurate diagnosis of active TB is …

Key Points HIV-Associated Tuberculosis Almost half of inpatients with human
immunodeficiency virus (HIV)–associated tuberculosis in countries with a high disease …

Interrupting transmission events is critical to tuberculosis control. Cough-generated aerosol
cultures predict tuberculosis transmission better than microbiological or clinical markers. We …

Rapid, accurate, sputum-free tests for tuberculosis (TB) triage and confirmation are urgently
needed to close the widening diagnostic gap. We summarise key technologies and review …

Background An estimated one fourth of the world's population is infected with
Mycobacterium tuberculosis, and 5–10% of those infected develop tuberculosis in their …

Background Since 2011, WHO has recommended that HIV-positive inpatients be routinely
screened for tuberculosis with the WHO four-symptom screen (W4SS) and, if screened …

Recent respiratory disease screening studies suggest promising performance of cough
classifiers, but potential biases in model training and dataset quality preclude robust …

New tuberculosis (TB) diagnostics are at a crossroads: their development, evaluation, and
implementation is severely damaged by resource diversion due to COVID-19. Yet several …

Background WHO recommends community-wide, systematic tuberculosis screening in high-
prevalence settings. C-reactive protein has been proposed as a tuberculosis screening tool …