Do ionic liquids exhibit the required characteristics to dissolve, extract, stabilize, and purify proteins? Past-present-future assessment

P Bharmoria, AA Tietze, D Mondal, TS Kang… - Chemical …, 2024 - ACS Publications
Proteins are highly labile molecules, thus requiring the presence of appropriate solvents and
excipients in their liquid milieu to keep their stability and biological activity. In this field, ionic …

Recent advances in the applications of ionic liquids in protein stability and activity: a review

R Patel, M Kumari, AB Khan - Applied biochemistry and biotechnology, 2014 - Springer
Room temperatures ionic liquids are considered as miraculous solvents for biological
system. Due to their inimitable properties and large variety of applications, they have been …

Functional self-assembling peptide nanofiber hydrogels designed for nerve degeneration

Y Sun, W Li, X Wu, N Zhang, Y Zhang… - … applied materials & …, 2016 - ACS Publications
Self-assembling peptide (SAP) RADA16-I (Ac-(RADA) 4-CONH2) has been suffering from a
main drawback associated with low pH, which damages cells and host tissues upon direct …

Room temperature ionic liquids meet biomolecules: a microscopic view of structure and dynamics

A Benedetto, P Ballone - ACS Sustainable Chemistry & …, 2016 - ACS Publications
Room temperature ionic liquids (RTILs) and biomolecules are both paradigmatic classes of
organic molecules, each consisting of a prodigious number of distinct chemical species …

Contemporary advancement of cholinium-based ionic liquids for protein stability and long-term storage: Past, present, and future outlook

A Sindhu, S Kumar, P Venkatesu - ACS Sustainable Chemistry & …, 2022 - ACS Publications
In the past two decades, ionic liquids (ILs) have been acknowledged as potentially attractive
“green” and “designer” solvents since their broader chemical space and the tunable nature …

Biocompatibility of ionic liquids towards protein stability: A comprehensive overview on the current understanding and their implications

A Kumar, M Bisht, P Venkatesu - International journal of biological …, 2017 - Elsevier
Over the past years since the discovery of ionic liquids (ILs), there is an increased demand
to consider ILs as novel biocompatible co-solvents for proteins. Due to their tunable physical …

Cholinium-based ionic liquids attenuate the amyloid fibril formation of lysozyme: a greener concept of antiamyloidogenic ionic liquids

A Sindhu, RS Varma, P Venkatesu - ACS Sustainable Chemistry …, 2022 - ACS Publications
Amyloid fibrils share dominant β-sheet structures that form pathological deposits in human
organs causing various debilitating neurodegenerative diseases such as type II diabetes …

Insights into protein-ionic liquid interactions aiming at macromolecule delivery systems

LK Harada, JFB Pereira, WF Campos… - Journal of the Brazilian …, 2018 - SciELO Brasil
Over the last few years, researchers have started to explore a particular class of compounds
defined as ionic liquids (ILs) in attempts to use their unique characteristics. Since ILs have a …

Self-assembling RATEA16 peptide nanofiber designed for rapid hemostasis

S Wei, F Chen, Z Geng, R Cui, Y Zhao… - Journal of Materials …, 2020 - pubs.rsc.org
Uncontrolled bleeding remains a contributor of mortality in various accidents, and ideal
hemostatic materials with rapid and efficient hemostasis, ease of use, biocompatibility and …

How does ultrasound-assisted ionic liquids (UA-ILs) pretreatment affect the functional properties of soy protein hydrolysates? A critical review.

W Zhang, ID Boateng, J Xu - Trends in Food Science & Technology, 2024 - Elsevier
Background Protein hydrolysates, a mixture of oligopeptides, polypeptides, and amino
acids, have numerous applications in the food industry. Soy protein hydrolysates (SPHs) …