Nanoparticle based delivery formulations have become a leading delivery strategy for
cancer imaging and therapy. The success of nanoparticle-based therapy relies heavily on …

It is generally accepted that metabolism is able to shape the immune response. Only
recently we are gaining awareness that the metabolic crosstalk between different tumor …

The semaphorins were initially characterized as axon guidance factors, but have
subsequently been implicated also in the regulation of immune responses, angiogenesis …

Glioma growth and progression are characterized by abundant development of blood
vessels that are highly aberrant and poorly functional, with detrimental consequences for …

Objective The effect of CA125, neutrophil to lymphocyte ratio (NLR) and thrombocytosis on
survival has been studied in ovarian cancer. This study explores the link between these …

Research over the last decades has provided strong evidence for the pivotal role of the
tumor-associated blood and lymphatic vasculature in supporting immunoevasion and in …

Breast cancer is the leading cause of cancer death in female. Until now, advanced breast
cancer is still lack effective treatment strategies and reliable prognostic markers. In the …

Glioblastoma (GB) is the most common and aggressive primary brain tumor, with poor
patient survival and lack of effective therapies. Late advances trying to decipher the …

Semaphorins are a large class of secreted or membrane-bound molecules. It has been
reported that semaphorins play important roles in regulating several hallmarks of cancer …

Hypoxia, a condition of oxygen deprivation, is considered a hallmark of tumor
microenvironment regulating several pathways and promoting cancer progression and …