An insight into the therapeutic potential of quinazoline derivatives as anticancer agents
I Ahmad - MedChemComm, 2017 - pubs.rsc.org
Cancer is one of the major causes of worldwide human mortality. A wide range of cytotoxic
drugs are available on the market, and several compounds are in different phases of clinical …
drugs are available on the market, and several compounds are in different phases of clinical …
Medicinal chemistry of quinazolines as anticancer agents targeting tyrosine kinases
MF Zayed - Scientia Pharmaceutica, 2023 - mdpi.com
Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …
Design, synthesis, characterization, enzymatic inhibition evaluations, and docking study of novel quinazolinone derivatives
K Pedrood, M Sherafati… - International Journal of …, 2021 - Elsevier
In this study, novel quinazolinone derivatives 7a-n were synthesized and evaluated against
metabolic enzymes including α-glycosidase, acetylcholinesterase, butyrylcholinesterase …
metabolic enzymes including α-glycosidase, acetylcholinesterase, butyrylcholinesterase …
Synthesis, characterization, in vitro antimicrobial and cytotoxic evaluation of Co (II), Ni (II), Cu (II) and Zn (II) complexes derived from bidentate hydrazones
Abstract Co (II), Ni (II), Cu (II) and Zn (II) complexes have been synthesized from hydrazone
ligands (HL 1–HL 4) obtained by condensation reaction of 6-chlorothiochroman-4-one with …
ligands (HL 1–HL 4) obtained by condensation reaction of 6-chlorothiochroman-4-one with …
Synthesis, characterization and apoptotic activity of quinazolinone Schiff base derivatives toward MCF-7 cells via intrinsic and extrinsic apoptosis pathways
The current study investigated the cytotoxic effect of 3-(5-chloro-2-hydroxybenzylideneamino
)-2-(5-chloro-2-hydroxyphenyl)-2, 3-dihydroquinazolin-41 (H)-one (A) and 3-(5-nitro-2 …
)-2-(5-chloro-2-hydroxyphenyl)-2, 3-dihydroquinazolin-41 (H)-one (A) and 3-(5-nitro-2 …
Insighting the inhibitory potential of new diorganotin (IV) complexes derived from tridentate ligands: Synthesis, structural elucidation and biological evaluation
In the present study, a series of diorganotin (IV) complexes (1–20) with the general formula
R 2 SnL 1-4 were synthesized by the reaction of R 2 SnCl 2 (R= Me, Et, Bu, and Ph) with the …
R 2 SnL 1-4 were synthesized by the reaction of R 2 SnCl 2 (R= Me, Et, Bu, and Ph) with the …
Remarkably flexible quinazolinones—synthesis and biological applications
MM Reddy, A Sivaramakrishna - Journal of Heterocyclic …, 2020 - Wiley Online Library
Even though several quinazolinone derivatives have been synthesized, still there is a
constant demand for designing and synthesis of new quinazolinone derivatives by fine …
constant demand for designing and synthesis of new quinazolinone derivatives by fine …
Development of novel ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitors for tumor immunotherapy
X Wang, X Lu, D Yan, Y Zhou, X Tan - International Journal of Molecular …, 2022 - mdpi.com
The cyclic guanosine monophosphate–adenosine monophosphate synthase–stimulator of
interferon genes–TANK-binding kinase 1–interferon regulating factor 3 (cGAS-STING-TBK1 …
interferon genes–TANK-binding kinase 1–interferon regulating factor 3 (cGAS-STING-TBK1 …
Pentacoordinated diorganotin (IV) complexes of Schiff base ligands: synthesis, characterization, antimicrobial and anticancer studies
In the present research work, a series of diorganotin (IV) complexes formulated as R2SnL1−
5 (where R is butyl, methyl, phenyl and L1− 5 are Schiff base ligands which were prepared …
5 (where R is butyl, methyl, phenyl and L1− 5 are Schiff base ligands which were prepared …
Synthesis of benzo [4, 5] imidazo [1, 2-a] pyrimidines and 2, 3-dihydroquinazolin-4 (1 H)-ones under metal-free and solvent-free conditions for minimizing waste …
PH Tran, TPT Bui, XQB Lam, XTT Nguyen - RSC advances, 2018 - pubs.rsc.org
Brønsted acidic ionic liquid was found to be an efficient and recyclable catalyst for the
synthesis of benzo [4, 5] imidazo [1, 2-a] pyrimidines and 2, 3-dihydroquinazolin-4 (1H) …
synthesis of benzo [4, 5] imidazo [1, 2-a] pyrimidines and 2, 3-dihydroquinazolin-4 (1H) …